ONCOFLORA


GUT MICROBIOTA, A PREDICTIVE ORGAN, AND A NEW APPROACH TO SUPPORT YOUR RESEARCHES IN ONCOLOGY.
Learn how Oncoflora offers real added value to your Oncology R&D by:

  • Developing new treatments and new nutritional diets/b>
  • Increasing efficacy and reducing side effects of cancer therapeutics
  • Better understanding cancer development to adapt new effective responses



Rely on our knowledge of the microbiome for increasing success rates in oncology:

A better understanding of the microbiota can lead to significant improvements in cancer treatment, and strong benefits for cancer patients, because Microbiota:

  • Interacts with the host and cancer
  • Is an important environmental factor (>2kg of bacteria)
  • Is a key component of metabolism, drug absorption and immunity

Multifunctional contribution of the microbiota to cancer hallmarks:

  • Sustaining tumor proliferative signaling
  • Avoiding tumor immune destruction
  • Tumorpromoting inflammation

An array of opportunities for translational research:

  • Pharmacological evaluation of anticancer therapies
  • Prediction of treatment side effects (diarrhea, skin rash...)
  • Identification of clusters of microbiota enterotypes as biomarkers
  • Clinical patient stratification
  • Evaluation of microbiota homeostasis modulators
  • Anticachexia compound evaluation

The Tool Box:

  • Stool, serum and tumor sampling and biobanking
  • Metagenomic analysis of the microbiota
  • Richness and diversity of microbiota enterotype quantification
  • PatientDerived Xenograft tumor models
  • Humanized in vivo models
  • Syngenic models
  • Clinical and preclinical pharmacology of anticancer drugs (PK / PD, drug combinations...)

Our approach can contribute to:

  • Increasing personalized treatment efficacy
  • Decreasing toxicity and resistance
  • Enhancing bioavailability of drugs
  • Adapting diet to new treatments
  • Increasing the quality of life of cancer patients



For more information email:
efang@oncodesign.com - biofortiscontact@mxns.com
www.oncodesign.com - www.biofortis.eu
Oncodesign® Biotechnology was founded by Dr Philippe Genne in Dijon, France, in 1995 to discover new and effective approaches to cancer treatment.
To reach this objective, we have developed two strategic activities: Experimentation of new cancer therapies (fee-for-service) and drug / biomarker Discovery programs in partnership with the pharmaceutical industry.
 
biofortis-small